Previous studies have indicated that early exposure to complex foreign proteins, such as cow’s milk proteins, increases the risk of type 1 diabetes in individuals with genetic risk for type 1 diabetes.
“In 2002, we therefore embarked on a large-scale study on 2159 infants with a family member affected by type 1 diabetes and with genetic risk for type 1 diabetes to find an answer to the question whether delaying the exposure to complex foreign proteins will decrease the risk of diabetes”, says Professor Mikael Knip from the University of Helsinki, the leader of the international TRIGR Study.
After breastfeeding, infants were weaned either to a special formula (extensively hydrolyzed casein formula), with the cow’s milk proteins split into small peptides (small pieces of the protein), or to a regular cow’s milk based formula with intact cow’s milk proteins.
Infants received the study formula for at least 2 months until the age of 6-8 months and at the same time avoided cow´s milk proteins from all other food sources. All subjects were followed for at least 10 years to assess the numbers of children who developed diabetes.
The results show that in this large international randomized trial weaning to an extensively hydrolyzed casein formula during infancy did not result in a reduction in the incidence of type 1 diabetes compared to regular intact cow’s-milk-based formula after about 11.5 years of follow up.
Accordingly there is no evidence to revise the current dietary recommendations for infants at high risk for type 1 diabetes.
The findings have been published in the journal JAMA.
Originally published at The Asian Age
This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Diabetes-Cure.me and the submitting author have used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Please read our full Disclaimer.
Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for “FAIR USE” for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favour of fair use. Please read our full Disclaimer.